The National Academies of Sciences, Engineering and Medicine

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Jan. 10, 2019
Brief Summary of Second Summit Now Available

Second International Summit on Human Genome Editing: Continuing the Global Discussion, a new publication from the U.S. National Academies of Sciences, Engineering, and Medicine, provides a brief summary of presentations and discussions that took place last November at the Second International Summit on Human Genome Editing.

Nov. 29, 2018
Concluding Statement Issued

The organizing committee for the Second International Summit on Human Genome Editing issued a statement at the conclusion of the summit. Read More  

Nov. 27, 2018
Human Genome Editing Summit Kicks Off in Hong Kong

Carrie Lam, Hong Kong’s chief executive, welcomed hundreds of participants from around the world to the Second International Summit on Human Genome Editing, which began today. 

Hong Kong is honored to be hosting this prestigious group of scientists and experts from around the world,” Lam said at the three-day summit, being held on the campus at the University of Hong Kong. She noted that the acceleration of genome editing research that has occurred since the first international summit in 2015 in Washington D.C. makes it an opportune time to reconsider the science, ethics, and governance of this emerging area of research and applications.    

Nov. 26, 2018
Statement from the Organizing Committee Regarding Reported Human Embryo Genome Editing

On the eve of the Second International Summit on Human Genome Editing, we were informed of the birth of twins in China whose embryonic genomes had been edited. The researcher who led the work, He Jainkui, is scheduled to speak at the summit on Wednesday.

Nov. 21, 2018
Webcast: Second International Summit on Human Genome Editing

Tune in Tuesday, Nov. 27, at  8:30 a.m. HKT [Monday, Nov. 26, at 7:30 p.m. EST] for the live webcast of the Second International Summit on Human Genome Editing. Full Agenda | Summit Webcast

Oct. 30, 2018
Updated Agenda Now Available for Nov. 27-29 Second International Human Genome Editing Summit in Hong Kong

The full agenda is now available for the Second International Summit on Human Genome Editing, which will take place Nov. 27-29 in Hong Kong. The three-day summit will be co-hosted by the Academy of Sciences of Hong Kong, the Royal Society of London, the U.S. National Academy of Sciences, and the U.S. National Academy of Medicine. The summit will be held in the Grand Hall of the Lee Shau Kee Lecture Centre at the University of Hong Kong. For more information, visit the summit website.  

March 5, 2018
Now Available: Archived February Webinar About Developments and Advancements in Human Genome Editing

With the recent scientific advances making genome editing more efficient, precise, and flexible than ever before came an explosion of interest from around the globe in the possible ways human genome editing can improve human health. As part of the Human Gene-Editing Initiative, the National Academy of Sciences and National Academy of Medicine released a last year exploring the scientific underpinnings of human gene-editing technologies, their potential applications in biomedical research and medicine, and the clinical, ethical, legal, and social implications of their use.

On Thursday, Feb. 22, 2018, NAS/NAM and the Biotechnology Innovation Organization (BIO) co-hosted a webinar to learn about issues and recommendations discussed in the 2017 NAS/NAM report, breakthroughs and next steps in gene editing of somatic cells, and the regulatory framework for therapies that make use of genome editing.

Participants in the webinar included:

Matthew Porteus, Stanford University (consensus study committee member)
Sandy Macrae, Sangamo Therapeutics
Peter Marks, U.S. Food and Drug Administration

Click here for the archived webinar | Slides from the webinar

Nov. 17, 2017
ISSR Session on CRISPR/Cas and Human Germline Gene Editing 

calls for inclusive public discussion and debate about the potential uses of technologies such as CRISPR/Cas9 to make changes to human DNA. Engaging diverse viewpoints will be particularly critical to debates about uses that would raise complex societal and ethical issues, such as the creation of heritable genetic changes (also referred to as germline genome editing). 

With support from NAM's Kellogg Health of the Public Fund, the National Academies were pleased to support a webcast of “CRISPR/Cas and Human Germline Gene Editing: Possibilities and Perspectives,” a session during the International Society of Science and Religion (ISSR) meeting, held in association with the annual meeting of the American Academy of Religion in Boston on Nov. 17, 2017.  Speakers were NAS/NAM committee chair Richard Hynes, committee member John H. Evans, and  Ronald Cole Turner and Laurie Zoloth.

Feb. 14, 2017
Consensus Report to Be Released

Human Genome Editing: Science, Ethics, and Governance, the new report of the NAS-NAM Human Gene Editing Initiative, will be publicly released on Tuesday, Feb. 14. Members of the committee that wrote the report will present their findings and recommendations at a public briefing beginning at 11 a.m. EST in the Lecture Room of the National Academy of Sciences building, 2101 Constitution Ave., N.W., Washington, D.C. Those who cannot attend may view a live webcast.

March 7, 2016
Upcoming Public Meeting in Paris

The consensus committee will host a public meeting in Paris on April 29 focusing on the principles underlying human gene editing governance and policy. This event will be held one day after a workshop on the current scientific activities and regulatory landscape for human gene editing in the European Union, organized by the Federation of European Academies of Medicine. Both meetings will be held at the French National Academy of Medicine. '' to receive updates about the meeting agendas, speakers, and webcast availability.

March 7, 2016
Slides and Videos from the February Meeting

On Feb. 11, the NAS/NAM Human Gene Editing consensus committee heard input from select stakeholder groups, including public engagement experts, affected communities, industry, regulatory bodies, and members of the public who came to share their perspectives. Presentation slides and recorded videos of the talks and discussions are now .

Feb. 8, 2016
Summary of International Summit Now Available

A Meeting in Brief is now available that summarizes the December International Summit on Human Gene Editing.

Feb. 1, 2016
Consensus Study - Feb. 11 Public Meeting

NAS/NAM consensus study committee is holding an information-gathering meeting on Thursday, Feb. 11. Invited experts will discuss perspectives from the Sickle Cell Foundation of Tennessee, Parent Project Muscular Dystrophy, District of Columbia Association of the Deaf, and other potentially affected groups; how public attitudes and decision making intersect with science policy; and the potential for developing therapeutics using gene-editing technologies. Tune in for the live webcast.  

Dec. 8, 2015
Study on Human Gene Editing Begins

NAS and NAM are now moving forward with the second component of the Academies' Human Gene Editing Initiative, an in-depth, comprehensive review of the science and policy of human gene editing. 

Dec. 3, 2015
International Summit Concludes

The U.S. National Academy of Sciences, U.S. National Academy of Medicine, Chinese Academy of Sciences, and the U.K.'s Royal Society co-hosted a three-day international summit where global experts discussed the scientific, ethical, and governance issues associated with these new and emerging human gene-editing technologies. Visit the summit page for photos, videos, and much more.

Nov. 9, 2015
Agenda for International Summit Available; Media Registration Open

Registration for the media and for the general public to attend the three-day international summit is now open. At the summit, experts will discuss the scientific, ethical, and governance issues associated with these new and emerging human gene-editing technologies. Seating is limited; reporters must register in advance. [Public Registration is now Closed]

Draft Agenda Available

Oct. 19, 2015
Videos Available From Human Gene Editing Information-Gathering Meeting

To inform a committee planning the December international summit on human gene editing, NAS and NAM held a meeting on Oct. 5 to provide an overview of the state of the science. are now available of presentations from the event.

Sept. 25, 2015
Human Gene Editing Information-Gathering Meeting on Oct. 5

To inform a committee that is planning the December international summit on human gene editing, NAS and NAM are holding a meeting on Oct. 5 to provide an overview of the state of the science. Invited experts will discuss human gene-editing technologies, their efficiency and utility, the historical context of embryo and gene manipulation, approaches to treat and prevent genetic diseases, and China’s contributions to gene-editing research.  | Agenda

Sept. 14, 2015
Chinese Academy and Royal Society to Join in Convening International Summit; Organizing Committee Named

The Chinese Academy of Sciences and the U.K.'s Royal Society are joining NAS and NAM in co-hosting an international summit on human gene editing to be held Dec. 1-3 in Washington, D.C. An organizing committee has been appointed. 

June 16, 2015
NAM President Testifies at Hill Hearing

The House Subcommittee on Research and Technology held a hearing where NAM President Victor J. Dzau provided testimony about the Academies’ initiative.  | 

June 15, 2015
Advisory Group Named

An advisory group was announced today to counsel the NAS and NAM presidents on their new initiative on human gene editing.  

May 18, 2015
NAS and NAM Announce New Initiative

Olivierclement of Sciences and National Academy of Medicine launched a major initiative regarding human gene-editing research.  




About This Initiative

Powerful new gene-editing technologies, such as CRISPR-Cas9, hold great promise for advancing science and treating disease, but they also raise concerns and present complex challenges, particularly because of their potential to be used to make genetic changes that could be passed on to future generations, thereby modifying the human germline.

In keeping with the Academies' past leadership on controversial new areas of genetic research, such as recombinant DNA technology, human embryonic stem cell research, human cloning, and “gain-of-function” research, the National Academy of Sciences and the National Academy of Medicine's Human Genome Editing Initiative will provide researchers, clinicians, policymakers, and societies around the world with a comprehensive understanding of human gene editing to help inform decision-making about this research and its application.

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