Chronic homelessness is a highly complex social problem affecting communities around the country. The scope of the problem is substantial, with an estimated nearly 87,000 individuals experiencing chronic homelessness in 2017. The report addresses a fundamental question: To what extent have permanent supportive housing programs improved health outcomes and affected health care costs in people experiencing homelessness? The report also describes policy and program barriers that affect the ability to bring the permanent supportive housing programs and other housing models to scale to address housing and health care needs. This report will stimulate research and federal action to move the field forward and advance efforts to address chronic homelessness and improved health in this country.